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The battle against cancer is being fought on many fronts. Among the most cutting-edge research efforts are attempts to engineer nanotechnology-based therapies. To aid in this endeavor, the Nanotechnology Characterization Laboratory, part of the National Cancer Institute’s Alliance for Nanotechnology in Cancer and the National Cancer Institute at Frederick, has developed methods for nanoparticle…, E2524, , Test Method for Analysis of Hemolytic Properties of Nanoparticles, -E2524 is a protocol for examining the destruction of red blood cells (hemolysis) that can lead to anemia, jaundice and other issues. All intravenously administered drugs must be examined to determine potential for hemolysis. • , E2525, , Test Method for Evaluation of the Effect of Nanoparticulate Materials on the Formation of Mouse Granulocyte-Macrophage Colonies, -E2525 describes a method for evaluating nanoparticle stimulation or inhibition of the maturation of certain bone marrow cells (macrophages). A common side effect of anti-cancer drugs is inhibition of this process, and bone marrow cells may be particularly sensitive to nano-scale material. • , E2526, , Test Method for Evaluation of Cytotoxicity of Nanoparticulate Materials on Porcine Kidney Cells and Human Hepatocarcinoma Cells, -Because studies have indicated that many nanoparticles are cleared from the body through the kidney or liver, these organs are good choices for target organ toxicity evaluation. E2526 presents a method for evaluation of nanomaterial toxicity by examining effects on kidney and cancerous liver cells. Martin Fritts is senior principal scientist at the Nanotechnology Characterization Laboratory and…
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Members of ASTM International Committee F40 on Declarable Substances in Materials now have free access to a powerful regulatory database that houses all regulations related to Declarable Substances. F40 members who log in to their MyASTM page on the ASTM International Web site ( www.astm.org ) will find a link to the Enhesa database. Enhesa is a global environmental, health and safety…
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Changes in the composition of glass that recyclers receive has led to the need for a simple, quick and accurate method of sorting out incoming waste glass that contains arsenic, lead and other heavy metals. ASTM International Committee F40 on Declarable Substances in Materials is working on a proposed standard, WK15289 , Test Methods for Analysis of Heavy Metals in Glass Using X-Ray Fluorescence…
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Participation is being sought for the development of a proposed new standard, WK15434 , Test Method for Analysis of Tin-Based Solder Alloys Using Optical Emission Spectrometry. The proposed standard is being developed by Subcommittee F40.01 on Test Methods, which is part of ASTM International Committee F40 on Declarable Substances in Materials. According to Dirk Wissmann, product manager,…
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ASTM International’s Committee E13 on Molecular Spectroscopy and Separation Science will hold its February meeting in conjunction with the 58th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (Pittcon 2007) from Feb. 25-27 at the McCormick Place Convention Center in Chicago, Ill. All E13 meetings will be held in room N-129. During the conference and exhibit portion of…
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ASTM International Committee F40 on Declarable Substances in Materials has recently approved its second standard, F 2577 , Guide for Assessment of Materials and Products for Declarable Substances. The guide, which is under the jurisdiction of Subcommittee F40.02 on Management Practices and Guides, follows F 2576 , Terminology Relating to Declarable Substance in Materials, which was approved in…
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ASTM International Committee E56 on Nanotechnology has approved its first standard, E 2456 , Terminology for Nanotechnology. The new standard is under the jurisdiction of Subcommittee E56.01 on Terminology and Nomenclature. Because of the great need for a terminology document that is globally recognized and because of the cooperation of several organizations in making the document a reality,…
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According to Jerry Workman, chair of new ASTM International Subcommittee E13.16 on Chemical Sensors, one place to begin to understand the current and future importance of chemical sensors is the classic television show, Star Trek. “Mr. Spock, the science officer on the Starship Enterprise, routinely used his Tricorder to make measurements of atmospheric gases, soil samples, living tissue and…
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ASTM International Committee F40 on Declarable Substances in Materials has recently approved their first standard, F 2576 , Terminology Relating to Declarable Substances in Materials. The standard, which will serve as the committee’s lexicon of terms, abbreviations and units, is under the jurisdiction of Subcommittee F40.91 on Terminology. Nine terms are listed in the standard, which will be…
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ASTM International Subcommittee E13.15 on Analytical Data is currently working on a proposed new standard, WK6371, Analytical Information Markup Language (AnIML). Subcommittee E13.15 is under the jurisdiction of Committee E13 on Molecular Spectroscopy and Separation Science. AnIML is a markup language for describing analytical chemistry result data and metadata that can be used for data…