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Residual accelerator chemicals in medical gloves appear to be a leading cause of allergic contact dermatitis in health care workers. A new ASTM International standard allows rubber glove manufacturers to monitor the level of residual chemicals in their end products and to potentially make manufacturing changes to reduce allergen levels. The new standard, D7558 , Test Method for Colorimetric/…
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A revision to an important ASTM nanotechnology standard incorporates a large-scale interlaboratory study that took place in 2008. The revised standard, ASTM E2490 , Guide for Measurement of Particle Size Distribution of Nanomaterials in Suspension by Photon Correlation Spectroscopy (PCS), is under the jurisdiction of Subcommittee E56.02 on Characterization: Physical, Chemical and Toxicological…
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Once approved, a proposed new ASTM standard would provide the U.S. Food and Drug Administration and personal lubricant manufacturers a means to evaluate the effect of a lubricant on the physical integrity of condoms. No standard currently exists for this type of testing. Manufacturers of condoms and rubber gloves as well as personal lubricants are welcome to join in the development of ASTM…
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While drug products must be tested for chemical and physical stability in their market packages, the testing process can be long and expensive. A proposed new ASTM International standard under the jurisdiction of Committee D10 on Packaging will provide a quick and accurate method to minimize the necessary package testing. The proposed standard, WK21601 , Test Method for Measuring Water Vapor…
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While the use of radio frequency identification transponders has become common for inventory tracking purposes, RFID system performance can be affected by product and packaging materials. A new ASTM standard can be used to provide a framework for testing RFID system performance that can be applied to, and compared across, all RFID manufacturer systems in any industrial application that involves a…
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The growing number and severity of healthcare association infections has increased interest in standardization efforts for antimicrobial gloves. In order to explore this area, ASTM International Committee D11 on Rubber has created a new task group on antimicrobial medical gloves. Glove suppliers, manufacturers and distributors, as well as contract test labs, government agency…
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The need to create a more realistic simulation for the small parcel shipping and handling environment was the impetus for the development of a new ASTM standard, D7386 , Practice for Performance Testing of Packages for Single Parcel Delivery Systems. Subcommittee D10.21 on Shipping Containers and Systems—Application of Performance Test Methods, under the jurisdiction of ASTM International…
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A workshop on the role of standards in the emerging field of nanotechnology will be held Oct. 8-9, 2008, at the National Institute of Standards and Technology near Washington, D.C. The workshop, "Enabling Standards for Nanomaterial Characterization," is being co-sponsored by the National Cancer Institute's Nanotechnology Characterization Laboratory, the National Institute of Standards and…
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Responding to requests from the food service industry, ASTM International Committee D11 on Rubber has developed and approved a new standard, D7329 , Specification for Food Preparation and Food Handling (Food Service) Gloves. The new standard, under the jurisdiction of Subcommittee D11.40 on Consumer Rubber Products, will serve as a referee and guide to glove manufacturers, distributors and the…
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The battle against cancer is being fought on many fronts. Among the most cutting-edge research efforts are attempts to engineer nanotechnology-based therapies. To aid in this endeavor, the Nanotechnology Characterization Laboratory, part of the National Cancer Institute’s Alliance for Nanotechnology in Cancer and the National Cancer Institute at Frederick, has developed methods for nanoparticle…, E2524, , Test Method for Analysis of Hemolytic Properties of Nanoparticles, -E2524 is a protocol for examining the destruction of red blood cells (hemolysis) that can lead to anemia, jaundice and other issues. All intravenously administered drugs must be examined to determine potential for hemolysis. • , E2525, , Test Method for Evaluation of the Effect of Nanoparticulate Materials on the Formation of Mouse Granulocyte-Macrophage Colonies, -E2525 describes a method for evaluating nanoparticle stimulation or inhibition of the maturation of certain bone marrow cells (macrophages). A common side effect of anti-cancer drugs is inhibition of this process, and bone marrow cells may be particularly sensitive to nano-scale material. • , E2526, , Test Method for Evaluation of Cytotoxicity of Nanoparticulate Materials on Porcine Kidney Cells and Human Hepatocarcinoma Cells, -Because studies have indicated that many nanoparticles are cleared from the body through the kidney or liver, these organs are good choices for target organ toxicity evaluation. E2526 presents a method for evaluation of nanomaterial toxicity by examining effects on kidney and cancerous liver cells. Martin Fritts is senior principal scientist at the Nanotechnology Characterization Laboratory and…