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The battle against cancer is being fought on many fronts. Among the most cutting-edge research efforts are attempts to engineer nanotechnology-based therapies. To aid in this endeavor, the Nanotechnology Characterization Laboratory, part of the National Cancer Institute’s Alliance for Nanotechnology in Cancer and the National Cancer Institute at Frederick, has developed methods for nanoparticle…, E2524, , Test Method for Analysis of Hemolytic Properties of Nanoparticles, -E2524 is a protocol for examining the destruction of red blood cells (hemolysis) that can lead to anemia, jaundice and other issues. All intravenously administered drugs must be examined to determine potential for hemolysis. • , E2525, , Test Method for Evaluation of the Effect of Nanoparticulate Materials on the Formation of Mouse Granulocyte-Macrophage Colonies, -E2525 describes a method for evaluating nanoparticle stimulation or inhibition of the maturation of certain bone marrow cells (macrophages). A common side effect of anti-cancer drugs is inhibition of this process, and bone marrow cells may be particularly sensitive to nano-scale material. • , E2526, , Test Method for Evaluation of Cytotoxicity of Nanoparticulate Materials on Porcine Kidney Cells and Human Hepatocarcinoma Cells, -Because studies have indicated that many nanoparticles are cleared from the body through the kidney or liver, these organs are good choices for target organ toxicity evaluation. E2526 presents a method for evaluation of nanomaterial toxicity by examining effects on kidney and cancerous liver cells. Martin Fritts is senior principal scientist at the Nanotechnology Characterization Laboratory and…
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ASTM International Committee F24 on Amusement Rides and Devices will celebrate its 30th anniversary this year, marking its significant contributions to the global amusement industry. ASTM is one of the largest voluntary standards development organizations in the world., F24 Standards: The Foundation for Safe Fun, Since 1978, ASTM Committee F24 has developed the standards that are the underpinning of safety for amusement rides and attractions around the world. During the past three decades, Committee F24 has contributed a comprehensive range of standards that cover design, manufacturing, maintenance, inspection and operations across traditional amusement rides, specialty rides and attractions, and water-…, F24: Global Experts Developing Internationally Accepted Standards, ASTM Committee F24 brings together global amusement industry stakeholders in a best-in-class standards development forum. Today, F24 comprises approximately 500 professionals from 23 countries across North America, South America, Europe and Asia. F24 members include ride designers and manufacturers, engineers, technicians, regulators, inspectors, park owners and operators, consumer advocacy…, Supporting Ride Innovation and Amusement Growth, As new categories of amusement rides have been introduced and grown in popularity, ASTM Committee F24 has kept pace by addressing emerging requirements for standards. In the last several years, new F24 subcommittees have been formed to address growth in areas such as water rides as well as specialty attractions like go-karts, inflatable amusement devices and bumper boats., A Model of Industry Cooperation, To help to establish worldwide consistency in major areas of ride safety standards, ASTM Committee F24 works in close partnership with other representative organizations of the global amusement industry, such as the International Association of Amusement Parks and Attractions (IAAPA). ASTM F24 and IAAPA bring together representatives from industry and standards bodies from around the world for…
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ASTM International Committee E56 on Nanotechnology has approved its first standard, E 2456 , Terminology for Nanotechnology. The new standard is under the jurisdiction of Subcommittee E56.01 on Terminology and Nomenclature. Because of the great need for a terminology document that is globally recognized and because of the cooperation of several organizations in making the document a reality,…
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The rapid growth and variety of rides being developed within the water park industry has created a need for new standards to regulate the design and installation of water slides. While individual states within the United States had created rules and guidelines for water slides, these often varied greatly from each other. A new standard developed by ASTM International Committee F24 on Amusement…
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Although ASTM International Committee E56 on Nanotechnology was just established this year, it has already begun an ambitious program of developing new standards. Committee E56 is currently developing the following proposed standards, which deal with environmental safety issues, hemolytic properties and particle size measurement. Interested parties are invited to participate in the development of…, WK8985, Guide for Handling Unbound Engineered Nanoparticles in Occupational Settings, Academic, government and industrial laboratories are currently performing nanotechnology research and development and the scope and breadth of this work is expected to grow dramatically. Manufacturing processes involving nanomaterials have begun and commercially available nano-based products have been introduced. All of this activity in the nanotechnology realm has created the need for the…, WK8997, Practice for Analysis of Hemolytic Properties of Nanoparticles, Subcommittee E56.02 on Characterization has begun working on proposed new standard WK8997, Practice for Analysis of Hemolytic Properties of Nanoparticles. This proposed standard would provide a suitable procedure for establishing the safety of nanoparticulate materials that will be used in vivo , such as nanoparticles for therapeutics and diagnostics. "Nanotechnology products will be used in…, For further technical information, contact Scott McNeil, director, Nanotechnology Characterization Laboratory, Frederick, Md. (phone: 301/846-6939; mcneils@ncifcrf.gov )., WK8705, Measurement of Particle Size Distribution of Nanomaterials in Suspension by Photon Correlation Spectroscopy (PCS), Subcommittee E56.02 was formed to answer questions regarding characterization, such as size and shape of materials. Another proposed new standard under the jurisdiction of Subcommittee E56.02 is WK8705, Measurement of Particle Size Distribution of Nanomaterials in Suspension by Photon Correlation Spectroscopy (PCS), which deals with the vital issue of size characterization. The purpose of the…
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Open Meetings and One-Day Workshop in May, The National Institute of Advanced Industrial Science and Technology (AIST) in Japan has become the latest organization to sign a partnership agreement with ASTM International to develop a terminology standard for nanotechnology. AIST is an Independent Administrative Institution (IAI) in association with the Japanese Ministry of Economy, Trade and Industry (METI). AIST represents an amalgamation…, Partnerships Prove Beneficial, An early priority for the recently formed ASTM International Committee E56 on Nanotechnology is the development of a globally relevant, industry-driven terminology standard. In an effort to facilitate this objective, ASTM International has signed partnership agreements with the Institute of Electrical & Electronics Engineers (IEEE), the American Society of Mechanical Engineers (ASME), NSF…, Attendance Encouraged at Open Meetings and Workshop, Interested individuals are encouraged to attend the next meeting of Committee E56, which will take place May 16-18, 2005, in Reno, Nev., at the Hilton Reno Resort. Following the meetings, on May 19, at the same hotel, Committee E56 will cosponsor a Workshop on Characterization of Nanomaterials for Medical and Health Applications. The workshop will provide a structured venue to address critical…
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ASTM International, one of the largest voluntary standards development organizations in the world, announced the formation of a new committee to develop international consensus standards, definitions, terminology, and procedures covering nanotechnology. A branch of science and engineering that deals with things smaller than 100 nanometers (1 nm equals one-billionth of a meter), nanotechnology may…, An early priority for Committee E56 is the development of a globally relevant, industry-driven terminology standard for nanotechnology. In an effort to facilitate this objective, ASTM has signed partnership agreements with the Institute of Electrical & Electronics Engineers (IEEE), the American Society of Mechanical Engineers (ASME), and NSF International. These agreements focus solely on the…
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ASTM International Committee F24 on Amusement Rides and Devices currently has the following new proposed standards under development:, WK526 Netting, Subcommittee F24.24 on Design and Manufacture is currently developing WK526, Practice for Design, Manufacture, Installation and Testing of Climbing Nets and Netting/Mesh Used in Childrens Play Areas, Safety and Attractions. The purpose of the proposed standard is to reduce life-threatening and debilitating injuries associated with netted areas and attractions. "The amusement industry needed…, WK529 Water Slide Structures, Safety is at the heart of proposed new standard WK529, Guide for Classification, Design, Manufacture, Construction, and Operation of Water Slide Structures. The proposed standard, which is under the jurisdiction of Subcommittee F24.70 on Water Related Amusement Rides and Devices, will apply to water slides installed in public places such as water parks, hotels, resorts, and amusement parks.…, WK1074 Interactive Aquatic Play Equipment, In addition to WK529, Subcommittee F24.70 is also working on proposed new standard WK1074, Practice for Manufacture, Construction, Operations, Maintenance, and Water Quality of Interactive Aquatic Play Equipment. The proposed standard applies to interactive aquatic play equipment located in and around re-circulated and potable water, including swimming pools, activity pools, wave pools, lazy…