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Analysts in laboratories that use regression-based methods to determine uncertainty in data and customers that request such measurements will be the primary users of a new standard recently approved by ASTM International Committee D19 on Water. ASTM D7366 , Practice for Estimation of Measurement Uncertainty for Data from Regression-Based Methods was developed by Subcommittee D19.02 on Quality…
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A workshop on the role of standards in the emerging field of nanotechnology will be held Oct. 8-9, 2008, at the National Institute of Standards and Technology near Washington, D.C. The workshop, "Enabling Standards for Nanomaterial Characterization," is being co-sponsored by the National Cancer Institute's Nanotechnology Characterization Laboratory, the National Institute of Standards and…
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The battle against cancer is being fought on many fronts. Among the most cutting-edge research efforts are attempts to engineer nanotechnology-based therapies. To aid in this endeavor, the Nanotechnology Characterization Laboratory, part of the National Cancer Institute’s Alliance for Nanotechnology in Cancer and the National Cancer Institute at Frederick, has developed methods for nanoparticle…, E2524, , Test Method for Analysis of Hemolytic Properties of Nanoparticles, -E2524 is a protocol for examining the destruction of red blood cells (hemolysis) that can lead to anemia, jaundice and other issues. All intravenously administered drugs must be examined to determine potential for hemolysis. • , E2525, , Test Method for Evaluation of the Effect of Nanoparticulate Materials on the Formation of Mouse Granulocyte-Macrophage Colonies, -E2525 describes a method for evaluating nanoparticle stimulation or inhibition of the maturation of certain bone marrow cells (macrophages). A common side effect of anti-cancer drugs is inhibition of this process, and bone marrow cells may be particularly sensitive to nano-scale material. • , E2526, , Test Method for Evaluation of Cytotoxicity of Nanoparticulate Materials on Porcine Kidney Cells and Human Hepatocarcinoma Cells, -Because studies have indicated that many nanoparticles are cleared from the body through the kidney or liver, these organs are good choices for target organ toxicity evaluation. E2526 presents a method for evaluation of nanomaterial toxicity by examining effects on kidney and cancerous liver cells. Martin Fritts is senior principal scientist at the Nanotechnology Characterization Laboratory and…
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Cyanide is routinely analyzed in water samples, often to demonstrate regulatory compliance; however, improper sample collection or pretreatment can result in significant positive or negative bias potentially resulting in unnecessary permit violations or undetected cyanide releases into the environment. Because of the importance and timeliness of these issues, ASTM Subcommittee D19.06 on Methods…
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While nearly all of the instrumentation employed in the field to measure radioactive materials or radiation exposure rates used to be in the hands of state radiological control agencies or federal government national response organizations, this is no longer the case. Now, law enforcement personnel, first responders and other professionals have radiation detection instruments, though they may not…
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ASTM International Committee D19 on Water will host a workshop on turbidity during the June Committee Week in Norfolk, Va. Subcommittee D19.07 on Sediment, Geomorphology and Open Channel Flow will present the workshop from 1:00 to 5:00 p.m. on June 26, 2007. According to Mike Sadar, D19 member and principal application scientist, Hach Company, Committee D19 has invested several years in the…
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ASTM International Committee E56 on Nanotechnology has approved its first standard, E 2456 , Terminology for Nanotechnology. The new standard is under the jurisdiction of Subcommittee E56.01 on Terminology and Nomenclature. Because of the great need for a terminology document that is globally recognized and because of the cooperation of several organizations in making the document a reality,…
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Although ASTM International Committee E56 on Nanotechnology was just established this year, it has already begun an ambitious program of developing new standards. Committee E56 is currently developing the following proposed standards, which deal with environmental safety issues, hemolytic properties and particle size measurement. Interested parties are invited to participate in the development of…, WK8985, Guide for Handling Unbound Engineered Nanoparticles in Occupational Settings, Academic, government and industrial laboratories are currently performing nanotechnology research and development and the scope and breadth of this work is expected to grow dramatically. Manufacturing processes involving nanomaterials have begun and commercially available nano-based products have been introduced. All of this activity in the nanotechnology realm has created the need for the…, WK8997, Practice for Analysis of Hemolytic Properties of Nanoparticles, Subcommittee E56.02 on Characterization has begun working on proposed new standard WK8997, Practice for Analysis of Hemolytic Properties of Nanoparticles. This proposed standard would provide a suitable procedure for establishing the safety of nanoparticulate materials that will be used in vivo , such as nanoparticles for therapeutics and diagnostics. "Nanotechnology products will be used in…, For further technical information, contact Scott McNeil, director, Nanotechnology Characterization Laboratory, Frederick, Md. (phone: 301/846-6939; mcneils@ncifcrf.gov )., WK8705, Measurement of Particle Size Distribution of Nanomaterials in Suspension by Photon Correlation Spectroscopy (PCS), Subcommittee E56.02 was formed to answer questions regarding characterization, such as size and shape of materials. Another proposed new standard under the jurisdiction of Subcommittee E56.02 is WK8705, Measurement of Particle Size Distribution of Nanomaterials in Suspension by Photon Correlation Spectroscopy (PCS), which deals with the vital issue of size characterization. The purpose of the…
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Open Meetings and One-Day Workshop in May, The National Institute of Advanced Industrial Science and Technology (AIST) in Japan has become the latest organization to sign a partnership agreement with ASTM International to develop a terminology standard for nanotechnology. AIST is an Independent Administrative Institution (IAI) in association with the Japanese Ministry of Economy, Trade and Industry (METI). AIST represents an amalgamation…, Partnerships Prove Beneficial, An early priority for the recently formed ASTM International Committee E56 on Nanotechnology is the development of a globally relevant, industry-driven terminology standard. In an effort to facilitate this objective, ASTM International has signed partnership agreements with the Institute of Electrical & Electronics Engineers (IEEE), the American Society of Mechanical Engineers (ASME), NSF…, Attendance Encouraged at Open Meetings and Workshop, Interested individuals are encouraged to attend the next meeting of Committee E56, which will take place May 16-18, 2005, in Reno, Nev., at the Hilton Reno Resort. Following the meetings, on May 19, at the same hotel, Committee E56 will cosponsor a Workshop on Characterization of Nanomaterials for Medical and Health Applications. The workshop will provide a structured venue to address critical…
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ASTM International, one of the largest voluntary standards development organizations in the world, announced the formation of a new committee to develop international consensus standards, definitions, terminology, and procedures covering nanotechnology. A branch of science and engineering that deals with things smaller than 100 nanometers (1 nm equals one-billionth of a meter), nanotechnology may…, An early priority for Committee E56 is the development of a globally relevant, industry-driven terminology standard for nanotechnology. In an effort to facilitate this objective, ASTM has signed partnership agreements with the Institute of Electrical & Electronics Engineers (IEEE), the American Society of Mechanical Engineers (ASME), and NSF International. These agreements focus solely on the…