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The battle against cancer is being fought on many fronts. Among the most cutting-edge research efforts are attempts to engineer nanotechnology-based therapies. To aid in this endeavor, the Nanotechnology Characterization Laboratory, part of the National Cancer Institute’s Alliance for Nanotechnology in Cancer and the National Cancer Institute at Frederick, has developed methods for nanoparticle…, E2524, , Test Method for Analysis of Hemolytic Properties of Nanoparticles, -E2524 is a protocol for examining the destruction of red blood cells (hemolysis) that can lead to anemia, jaundice and other issues. All intravenously administered drugs must be examined to determine potential for hemolysis. • , E2525, , Test Method for Evaluation of the Effect of Nanoparticulate Materials on the Formation of Mouse Granulocyte-Macrophage Colonies, -E2525 describes a method for evaluating nanoparticle stimulation or inhibition of the maturation of certain bone marrow cells (macrophages). A common side effect of anti-cancer drugs is inhibition of this process, and bone marrow cells may be particularly sensitive to nano-scale material. • , E2526, , Test Method for Evaluation of Cytotoxicity of Nanoparticulate Materials on Porcine Kidney Cells and Human Hepatocarcinoma Cells, -Because studies have indicated that many nanoparticles are cleared from the body through the kidney or liver, these organs are good choices for target organ toxicity evaluation. E2526 presents a method for evaluation of nanomaterial toxicity by examining effects on kidney and cancerous liver cells. Martin Fritts is senior principal scientist at the Nanotechnology Characterization Laboratory and…
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An innovative system that can be used to test and compare sediment control products has been approved as a new ASTM International standard by Committee D18 on Soil and Rock. The standard, D 7351 , Test Method for Determination of Sediment Retention Device Effectiveness in Sheet Flow Applications, is under the jurisdiction of Subcommittee D18.25 on Erosion and Sediment Control Technology. Even…
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A new ASTM standard, D 7401, Test Methods for Laboratory Determination of Rock Anchor Capacities by Pull and Drop Tests, is the result of requests to standardize a test to determine dynamic rock anchor capacity that is used internationally in the mining industry. The new test method was developed by Subcommittee D18.12 on Rock Mechanics, part of ASTM International Committee D18 on Soil and Rock.…
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A proposed new ASTM International standard will fill a need for a reliable method for measuring beryllium at various levels in soil samples that does not require the use of aggressive digestion methods involving strong acids. The proposed standard, WK17600 , Test Method for Determination of Beryllium in Soil, Rock, Sediment and Fly Ash Using Field-Based Extraction and Fluorescence Detection, is…
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A new standard recently approved by ASTM International Committee D18 on Soil and Rock is the result of requests from the Indiana Department of Transportation and the U.S. Bureau of Reclamation for an effective test method to cover the determination of the maximum dry unit weight and water content range for effective compaction of granular soils. D 7382 , Test Methods for Determination of Maximum…
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A new ASTM International standard, D 7367 , Test Method for Determining Water Holding Capacity of Fiber Mulches for Hydraulic Planting, will provide a means of evaluating water holding capacity in fiber mulches. The standard has been developed by Subcommittee D18.25 on Erosion and Sediment Control Technology, part of ASTM International Committee D18 on Soil and Rock. According to Becky Gauthier…
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A new ASTM International standard, D 7322 , Test Method for Determination of Rolled Erosion Control Product (RECP) Ability to Encourage Seed Germination and Plant Growth Under Bench-Scale Conditions, covers guidelines, requirements and procedures for evaluating the effect of RECPs on seed germination and vegetation enhancement. The standard was developed by Subcommittee D18.25 on Erosion and…
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An extensively revised standard and a proposed new standard are among the latest activities pursued by ASTM International Committee D18 on Soil and Rock. Subcommittee D18.11 on Deep Foundations has completed revisions to D 1143 , Test Method for Deep Foundations Under Static Axial Compressive Load, while Subcommittee D18.25 on Erosion and Sediment Control Technology is now working on proposed new…, ASTM D 1143, Test Method for Deep Foundations Under Static Axial Compressive Load, D 1143 covers procedures for testing vertical or inclined deep foundations individually or in groups to determine the axial deflection in response to a static axial compressive load. Subcommittee D18.11 has recently approved an extensive revision of D 1143 that reflects the latest technology used for these purposes. The following are the biggest changes to D 1143, according to Paul Bullock,…, WK13229, Test Method for Determination of Hydraulically Applied Fiber Matrix Performance in Protecting Hill Slopes from Rainfall-Induced Erosion, Subcommittee D18.25 is seeking participation in the ongoing development of WK13229 , particularly from testing laboratories and tackifier manufacturers/importers. WK13229 covers the guidelines, requirements and procedures for evaluating the ability of hydraulically applied fiber matrix to protect hill slopes from rainfall-induced erosion. For this protection to happen effectively, the fiber…
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ASTM International Committee B08 on Metallic and Inorganic Coatings has recently approved a revision of one of its most important standards, B 633 , Specification for Electrodeposited Coatings of Zinc on Iron and Steel. B 633 is under the jurisdiction of Task Group B08.08.04 on Soft Metals, which is part of Subcommittee B08.08 on Metallic Coatings. Zinc coatings are used to provide a sacrificial…
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ASTM International Committee D18 on Soil and Rock has recently approved a new standard, D 6938 , Test Methods for In-Place Density and Water Content of Soil and Soil-Aggregate by Nuclear Methods (Shallow Depth). The new standard, which is under the jurisdiction of Subcommittee D18.08 on Special and Construction Control Tests, consolidates the information contained in two other D18.08 standards, D…