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A workshop on the role of standards in the emerging field of nanotechnology will be held Oct. 8-9, 2008, at the National Institute of Standards and Technology near Washington, D.C. The workshop, "Enabling Standards for Nanomaterial Characterization," is being co-sponsored by the National Cancer Institute's Nanotechnology Characterization Laboratory, the National Institute of Standards and…
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The battle against cancer is being fought on many fronts. Among the most cutting-edge research efforts are attempts to engineer nanotechnology-based therapies. To aid in this endeavor, the Nanotechnology Characterization Laboratory, part of the National Cancer Institute’s Alliance for Nanotechnology in Cancer and the National Cancer Institute at Frederick, has developed methods for nanoparticle…, E2524, , Test Method for Analysis of Hemolytic Properties of Nanoparticles, -E2524 is a protocol for examining the destruction of red blood cells (hemolysis) that can lead to anemia, jaundice and other issues. All intravenously administered drugs must be examined to determine potential for hemolysis. • , E2525, , Test Method for Evaluation of the Effect of Nanoparticulate Materials on the Formation of Mouse Granulocyte-Macrophage Colonies, -E2525 describes a method for evaluating nanoparticle stimulation or inhibition of the maturation of certain bone marrow cells (macrophages). A common side effect of anti-cancer drugs is inhibition of this process, and bone marrow cells may be particularly sensitive to nano-scale material. • , E2526, , Test Method for Evaluation of Cytotoxicity of Nanoparticulate Materials on Porcine Kidney Cells and Human Hepatocarcinoma Cells, -Because studies have indicated that many nanoparticles are cleared from the body through the kidney or liver, these organs are good choices for target organ toxicity evaluation. E2526 presents a method for evaluation of nanomaterial toxicity by examining effects on kidney and cancerous liver cells. Martin Fritts is senior principal scientist at the Nanotechnology Characterization Laboratory and…
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Healthcare workers who inspect radiation protection garments will be the primary users of a proposed new ASTM International standard, WK15823 , Practice for the Fluoroscopic Inspection of Radiation Protection Garments. The proposed practice is being developed by Subcommittee F23.70 on Radiological Hazards, part of ASTM International Committee F23 on Protective Clothing. “Besides visual…
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Two proposed new standards currently being developed by ASTM International Committee F23 on Protective Clothing will each contribute to the safety of protective clothing. Interested parties are invited to participate in the development of both proposed standards, which are WK14247 , Specification for Air-Fed Protective Ensembles and WK14442 , Antimicrobial Activity of Textiles Following Multiple…, WK14247, Specification for Air-Fed Protective Ensembles, Subcommittee F23.30 on Chemicals invites users and manufacturers of air-fed protective ensembles to participate in the development of a proposed new standard WK14247 . This proposed specification would establish design, performance, documentation, labeling and certification requirements for protective ensembles that rely on principal air supply to the wearer via an air line or air filtered…, WK14442, Antimicrobial Activity of Textiles Following Launderings with Bleach, Antimicrobial treatments often are applied to textiles to impart durable efficacy, reducing the survival and growth of microorganisms on the textile. A proposed new ASTM standard, WK14442 , under the jurisdiction of F23’s biological subcommittee, F23.40 , would ensure these antimicrobial agents would continue to work throughout a garment’s life span. “Over the last 10 years, the industry has…
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ASTM International Committee E56 on Nanotechnology has approved its first standard, E 2456 , Terminology for Nanotechnology. The new standard is under the jurisdiction of Subcommittee E56.01 on Terminology and Nomenclature. Because of the great need for a terminology document that is globally recognized and because of the cooperation of several organizations in making the document a reality,…
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ASTM International Committee F23 on Personal Protective Clothing and Equipment has developed a new standard in response to a United States Food and Drug Administration ruling to change how the marketing of surgical gowns is regulated. The new standard, F 2407 , Specification for Surgical Gowns Intended for Use in Healthcare Facilities, is under the jurisdiction F23’s biological subcommittee, F23.…
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A new publication about the performance of protective clothing is now available from ASTM International. STP 1462, Performance of Protective Clothing: Global Needs and Emerging Markets, 8th Symposium , includes 19 peer-reviewed papers that address topics related to the performance of protective clothing for government and industrial workers, first responders, and civilians. A vital resource for…
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Fostering government support for ASTM International Committee F23 on Protective Clothing and other standards developing committees related to protective clothing is the central goal of a new memorandum of understanding recently signed by ASTM International and the National Institute for Occupational Health and Safety. The agreement highlights the role of the NIOSH National Personal Protective…
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Although ASTM International Committee E56 on Nanotechnology was just established this year, it has already begun an ambitious program of developing new standards. Committee E56 is currently developing the following proposed standards, which deal with environmental safety issues, hemolytic properties and particle size measurement. Interested parties are invited to participate in the development of…, WK8985, Guide for Handling Unbound Engineered Nanoparticles in Occupational Settings, Academic, government and industrial laboratories are currently performing nanotechnology research and development and the scope and breadth of this work is expected to grow dramatically. Manufacturing processes involving nanomaterials have begun and commercially available nano-based products have been introduced. All of this activity in the nanotechnology realm has created the need for the…, WK8997, Practice for Analysis of Hemolytic Properties of Nanoparticles, Subcommittee E56.02 on Characterization has begun working on proposed new standard WK8997, Practice for Analysis of Hemolytic Properties of Nanoparticles. This proposed standard would provide a suitable procedure for establishing the safety of nanoparticulate materials that will be used in vivo , such as nanoparticles for therapeutics and diagnostics. "Nanotechnology products will be used in…, For further technical information, contact Scott McNeil, director, Nanotechnology Characterization Laboratory, Frederick, Md. (phone: 301/846-6939; mcneils@ncifcrf.gov )., WK8705, Measurement of Particle Size Distribution of Nanomaterials in Suspension by Photon Correlation Spectroscopy (PCS), Subcommittee E56.02 was formed to answer questions regarding characterization, such as size and shape of materials. Another proposed new standard under the jurisdiction of Subcommittee E56.02 is WK8705, Measurement of Particle Size Distribution of Nanomaterials in Suspension by Photon Correlation Spectroscopy (PCS), which deals with the vital issue of size characterization. The purpose of the…
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Open Meetings and One-Day Workshop in May, The National Institute of Advanced Industrial Science and Technology (AIST) in Japan has become the latest organization to sign a partnership agreement with ASTM International to develop a terminology standard for nanotechnology. AIST is an Independent Administrative Institution (IAI) in association with the Japanese Ministry of Economy, Trade and Industry (METI). AIST represents an amalgamation…, Partnerships Prove Beneficial, An early priority for the recently formed ASTM International Committee E56 on Nanotechnology is the development of a globally relevant, industry-driven terminology standard. In an effort to facilitate this objective, ASTM International has signed partnership agreements with the Institute of Electrical & Electronics Engineers (IEEE), the American Society of Mechanical Engineers (ASME), NSF…, Attendance Encouraged at Open Meetings and Workshop, Interested individuals are encouraged to attend the next meeting of Committee E56, which will take place May 16-18, 2005, in Reno, Nev., at the Hilton Reno Resort. Following the meetings, on May 19, at the same hotel, Committee E56 will cosponsor a Workshop on Characterization of Nanomaterials for Medical and Health Applications. The workshop will provide a structured venue to address critical…